ISTU ON-AIR Webinar Series
March 2025
Microbubble Dynamics in Brain Microvessels — Insights into how ultrasound-driven microbubbles alter the blood-brain barrier permeability
by James Choi, Ph.D., Imperial College London, moderated by Meaghan O’Reilly, Ph.D. from Sunnybrook Research Institute and University of Toronto, hosted by Tatiana Khokhlova, ISTU Educational Committee Chair, University of Washington in Seattle
About the Professors
James J. Choi, Ph.D.
Department of Bioengineering
Imperial College London
Dr. Choi is an Associate Professor (SL) at the Department of Bioengineering at Imperial College London and leads the Non-invasive Surgery & Biopsy Laboratory. He received the B.S.E. degree in computer engineering at the University of Michigan, Ann Arbor, (USA) and a Ph.D. degree in Biomedical Engineering at Columbia University, (USA). In 2011, he then conducted postdoctoral research at the University of Oxford, (UK) as a Frederick V. Hunt Postdoctoral Research Fellow in Acoustics. In 2013, he founded the Non-invasive Surgery & Biopsy Laboratory at Imperial College London, London, United Kingdom, whose mission is to create the next generation of non-invasive microsurgical devices for the treatment and diagnosis of diseases. In 2022, he was awarded the Frederic Lizzi Award for his contributions to focused ultrasound methods for delivering drugs to the brain.
Meaghan O’Reilly, Ph.D.
Sunnybrook Research Institute
University of Toronto
Dr. O’Reilly is a Senior Scientist in Physical Sciences at Sunnybrook Research Institute in Toronto, and an Associate Professor of Medical Biophysics at the University of Toronto, and the tier 2 Canada Research Chair in Biomedical Ultrasound. Her research interests include delivery, monitoring and control of bubble-mediated therapies in the CNS, with a recent focus on targeted drug delivery to the spinal cord, and the development of devices and methods for transvertebral focusing at clinical scale.
About ISTU
The International Society for Therapeutic Ultrasound (ISTU) is a non-profit organization founded in 2001 to increase and diffuse knowledge of therapeutic ultrasound to the scientific and medical community, and to facilitate the translation of therapeutic ultrasound techniques into the clinical area for the benefit of patients worldwide.
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Keywords: brain microvessels, International Society for Therapeutic Ultrasound, ISTU, ISTU ON-AIR Webinar Series, James Choi, March 2025, Meaghan O’Reilly, microbubble dynamics, Microbubble Dynamics in Brain Microvessels, Shimadzu HyperVision HPV-X2, Tatiana Khokhlova, Ultra High-Speed Imaging